http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113740476-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_398b13b3030fd7dd247eaf1d2006aa58 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8872 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a6b4d8033eb59d9f8c7f0c32537d06e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d918cb2205150e3a38c098b842d7838 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e0558ccecdb27e3c7f00315cd75aee5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f001c0d8e226e38d6908fde09435965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc3c416c95326ac8711341ad1b6e061d |
| publicationDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113740476-A |
| titleOfInvention | Method for detecting content of impurity L-2-aminobutanamide hydrochloride in brivaracetam drug |
| abstract | The invention relates to a method for detecting the content of impurity L-2-aminobutanamide hydrochloride in a brivaracetam drug. The method for detecting the impurity L-2-aminobutanamide hydrochloride in the brivaracetam specifically comprises the following steps of: (1) preparing a test solution; (2) preparing a reference substance solution; (3) respectively sucking the test solution and the reference solution, injecting into a high performance liquid chromatograph, wherein the chromatographic conditions are as follows: a chromatographic column: octadecylsilane chemically bonded silica is used as a filling agent; mobile phase: the composite material consists of a phase A and a phase B, wherein the phase A is a sodium octane sulfonate solution, and the phase B is acetonitrile. The detection method can accurately detect the content of the L-2-aminobutanamide hydrochloride in the brivaracetam drug, effectively separate the chromatographic peak of the brivaracetam and the impurity L-2-aminobutanamide hydrochloride, improve the quality of the brivaracetam drug and have wide application prospect. |
| priorityDate | 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.