http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113736855-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db9efde660b78f98b102046e09d07ab7 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-682 |
filingDate | 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2db7590098d6c49b72b743dcd549359a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91bd6e4edc17acb4f03807d1077c7486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3b42bc00aab9c8dcf935c7ac2ac4b6e |
publicationDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113736855-A |
titleOfInvention | Method for detecting 5-hydroxymethylfurfural based on gold nanoparticle amplification QCM signal |
abstract | The invention discloses a method for detecting 5-Hydroxymethylfurfural (HMF) based on amplification QCM signals of gold nanoparticles, which comprises the steps of using gold nanoparticles with single-chain DNA (ssDNA) functionalization in a Quartz Crystal Microbalance (QCM) to detect 5-Hydroxymethylfurfural (HMF), preventing the formation of DNAzyme by utilizing mutual competition between aldehyde groups in an HMF molecular structure and aldehyde groups on an ES I chain, further influencing the cutting of the gold nanoparticles with the functionalized ssDNA, further influencing the hybridization with capture probe DNA (capture DNA) on a quartz crystal microbalance, changing the real-time frequency shift of the QCM, amplifying the QCM signals, and detecting the HMF by utilizing the QCM. The invention does not need expensive instruments, has simple operation, no mark and high sensitivity. |
priorityDate | 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.