http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113736855-A

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filingDate 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2db7590098d6c49b72b743dcd549359a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91bd6e4edc17acb4f03807d1077c7486
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publicationDate 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113736855-A
titleOfInvention Method for detecting 5-hydroxymethylfurfural based on gold nanoparticle amplification QCM signal
abstract The invention discloses a method for detecting 5-Hydroxymethylfurfural (HMF) based on amplification QCM signals of gold nanoparticles, which comprises the steps of using gold nanoparticles with single-chain DNA (ssDNA) functionalization in a Quartz Crystal Microbalance (QCM) to detect 5-Hydroxymethylfurfural (HMF), preventing the formation of DNAzyme by utilizing mutual competition between aldehyde groups in an HMF molecular structure and aldehyde groups on an ES I chain, further influencing the cutting of the gold nanoparticles with the functionalized ssDNA, further influencing the hybridization with capture probe DNA (capture DNA) on a quartz crystal microbalance, changing the real-time frequency shift of the QCM, amplifying the QCM signals, and detecting the HMF by utilizing the QCM. The invention does not need expensive instruments, has simple operation, no mark and high sensitivity.
priorityDate 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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