http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113735952-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85d4f414123bbd5630c990bd1ef1994b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate | 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20a4c1839b38946eded7edb79c200d77 |
| publicationDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113735952-A |
| titleOfInvention | A ground dragon protein EDA-R activator |
| abstract | The invention discloses an earthworm protein EDA-R activator, which is characterized in that: the earthworm protein EDA-R activator is a protein composed of an amino acid sequence shown in SEQ ID No. 6, and the components are: F-O The molecular weight of ‑1‑HM‑23 is: 1310±100 Daltons. The protein does not directly degrade fibrin activity, but significantly enhances fibrinolysis in vivo and promotes thrombolysis by activating EDA-R residues in vivo. The preparation method of the earthworm protein EDA-R activator uses earthworms after cleaning, nano-pulverization, hydrolysis, centrifugal separation, dialysis, gel chromatography and electrophoresis to separate and purify to obtain active components. Because the molecular weight of the earthworm protein EDA-R activator of the present invention is only about 1/20 of that of lumbrokinase, it has strong pharmacokinetic advantages, fast oral absorption, rapid onset of injection, and has a two-way regulatory effect without bleeding and bleeding. The side effects of prolonged coagulation time have broad application prospects, good economic value and social benefits. |
| priorityDate | 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.