http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113735890-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0816 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2021-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113735890-B |
| titleOfInvention | Cys fluorescent probe capable of avoiding interference of intracellular GSH (glutathione) and preparation and application thereof |
| abstract | The invention relates to the field of fluorescent probes, in particular to a Cys fluorescent probe capable of avoiding interference of intracellular GSH (glutathione) and preparation and application thereof. In recent years a series of highly selective Cys fluorescent probes have been developed in succession, which, although eliminating to some extent the interference of GSH-induced fluorescence signals, still do not effectively overcome the limitation of reduced sensitivity brought about by GSH-consuming probes. In order to solve the problems, the invention develops a specific Cys fluorescent probe which is not interfered by GSH, and preparation and application thereof, the fluorescent probe can directly react with Cys to generate large fluorescence off-on response, and the reaction product of the fluorescent probe and the GSH can be further replaced by Cys to generate the same fluorescent product and fluorescent response, thereby not only avoiding the interference of high-concentration GSH in cells on fluorescent signals, but also avoiding the consumption of the probe by the GSH. |
| priorityDate | 2021-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.