http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113730659-A

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filingDate 2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58ca9565e9600abf177778e09f92b7b0
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publicationDate 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113730659-A
titleOfInvention A kind of rare earth micro-nano material and chitin composite bone implant material and preparation method
abstract The invention discloses a rare earth micro-nano material and chitin composite bone implant material and a preparation method. The alkaline aqueous solution, rare earth micro-nano material and chitin powder are fully mixed through mechanical stirring and ultrasonic treatment to obtain a uniform mixed solution; The mixture was transferred to a polytetrafluoroethylene mold, placed in a freezer at ‑20℃ to ‑30℃, and then repeatedly freeze-thawed. After demolding, the chitin gel was obtained; Soak in water ethanol, take out and wash with deionized water until the washing becomes neutral to obtain composite bone implant material. In the invention, chitin is used as the matrix of the bone implant material, rare earth micro-nano materials are introduced, and the preparation conditions are optimized by a low-temperature freeze-thaw method to prepare a bone scaffold material with suitable pore size, high porosity, good mechanical strength and versatility. After drying, a hollow biomimetic structure similar to the bone marrow cavity can be formed, which is of great significance to the research of bone repair and regeneration.
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