http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113730642-B

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filingDate 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113730642-B
titleOfInvention Gradient elastic deformation differential drug release composite dressing and preparation method thereof
abstract The invention relates to a gradient elastic deformation differential drug release composite dressing and a preparation method thereof, comprising a gradient elastic deformation fabric and a drug-loaded hydrogel; regarding the gradient elastic deformation fabric as a plane structure, wherein the plane is formed by a concentric III region, a concentric II region and a concentric I region; gradient elastic deformation in a gradient elastic deformation fabric means: the maximum elastic deformation rates of the fabrics corresponding to the third area, the second area and the first area are sequentially reduced, and the maximum elastic deformation rate of the fabric corresponding to the third area is larger than the maximum deformation rate of the joint skin; the elastic modulus of the fabrics corresponding to the III area, the II area and the I area is increased in sequence. The drug-loaded hydrogel is combined with the gradient elastic deformation fabric and is positioned in the III region and the II region of the gradient elastic deformation fabric; the maximum elastic deformation rate of the drug-loaded hydrogel is greater than the maximum deformation rate of the joint skin. The dressing prepared by compounding the hydrogel and the fabric can generate differential drug release effect according to the tearing degree of the wound.
priorityDate 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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