http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113717354-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ae178fe5ea1fd193b8e5e1baf1ab3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76860418b52f9c22202206cbdf960a27 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G63-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-00 |
| filingDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b839a5ac31bfd7e95f9cbc350b9dc50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d89a6b6713de0ffe9f15905b9480210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0202eb2fa13c3d87cf49921c45cc546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beead3ae516cc10f1aac368d3101a5eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_294899e3b456c555b964f9139ab5727f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_751781803647c4f103ec554b1e9e213e |
| publicationDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113717354-A |
| titleOfInvention | A kind of amphiphilic polyester and its preparation method and use |
| abstract | The invention discloses an amphiphilic polyester and a preparation method and application thereof. In the present invention, tartaric acid, 1,3-dibromopropane and 1,6-adipic acid are used as raw materials, and dimethyl sulfoxide or N,N-dimethylformamide is used as raw materials. Three-step reaction; in the first step, the hydrophobic segment A and the hydrophilic segment B are synthesized respectively, wherein the terminal functional groups of the hydrophobic segment A and the hydrophilic segment B are different; in the second step, the hydrophobic segment A and the hydrophilic segment B are synthesized The water segment B is mixed and reacted for 24 hours; the conversion rate of the present invention is more than 90%. In addition, the final amphiphilic polyester can be assembled into nanomicelles in an aqueous solution, which can be loaded with drugs, especially hydrophobic drugs; at the same time, the polymer has excellent biocompatibility and biodegradability, and the raw materials used are natural Nontoxic. The advantages of the invention are: simple operation, easy-to-obtain raw materials, and preparation at room temperature. |
| priorityDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.