| abstract |
The present invention provides an MBMP2 protein composite hydrogel and a preparation method and application thereof. The preparation materials of the MBMP2 protein composite hydrogel include gelatin, agarose-MBMP2 composite microspheres and TG enzyme, and the preparation method includes the following Steps: (1) dissolving gelatin in water and adjusting pH to obtain a gelatin solution; (2) mixing the gelatin solution obtained in step (1) with agarose-MBMP2 composite microspheres, and then mixing with TG enzyme solution, and incubating to obtain The MBMP2 protein complex hydrogel. The MBMP2 protein composite hydrogel provided by the invention has good stability, simple preparation process, high biological safety, low cost, easy clinical operation, and can realize the effect of long-term sustained release of MBMP2. |