http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113698385-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2021-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113698385-B |
titleOfInvention | 2,2-disubstituted indolin-3-one alkaloid, its preparation method and application |
abstract | The invention discloses a 2,2-disubstituted indoline-3-one alkaloid, a preparation method and an application thereof, and belongs to the field of medicinal chemistry. The general structural formula of the 2,2-disubstituted indoline-3-one alkaloid is shown in (1), R 1 is a hydrogen atom, a halogen atom, an alkyl group with 1-4 carbons, and an alkyl group with 1-4 carbons. Carbon alkoxy, its position is monosubstituted at the 4-7 position of the benzene ring; R2 is an alkyl or ester group with 1-4 carbons, siloxy, halogen - substituted alkyl, phenyl, various Substituted phenyl, furyl, thienyl or pyridyl; R can be hydrogen, halogen, 1-4 carbon alkyl, 1-4 four-carbon alkoxy, 1-4 four-carbon alkane Oxycarbonyl, trifluoromethyl, phenyl, its position is the 5-8 position of quinoline ring monosubstituted. The compound has good antibacterial activity and can be used as an active ingredient to prepare a drug for treating bacterial infection. (1). |
priorityDate | 2021-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.