http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113679891-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 |
| filingDate | 2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113679891-B |
| titleOfInvention | A kind of ZIF-8 drug-loaded hydrogel osteopromoting scaffold, preparation method and application |
| abstract | The invention belongs to the technical field of metal-organic frameworks, and discloses a ZIF-8 drug-carrying hydrogel promoting bone scaffold, a preparation method and application thereof. The preparation method of the ZIF-8 drug-carrying hydrogel promoting bone support comprises: SIM@ZIF-8 Construction of drug-loading system and construction of SIM@ZIF-8/PEGDA/SA hydrogel; the new ZIF-8 drug-loaded hydrogel promotes bone scaffold is SIM@ZIF-8/PEGDA/SA. The present invention loads SIM (SIM@ZIF-8) in the ZIF-8 pore structure through an in-situ synthesis method, and improves the biochemical microenvironment of bone tissue to achieve the dual effect of reducing lipid and osteogenesis. In the present invention, ZIF-8 is loaded with SIM small-molecule drugs for the first time, and the final SIM@ZIF-8 system can reduce fat formation and promote osteogenesis under high-fat conditions, and has a good effect on the treatment of bone metabolic diseases caused by hyperlipidemia. application prospects. |
| priorityDate | 2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.