http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113679890-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 |
filingDate | 2021-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113679890-B |
titleOfInvention | A kind of heart valve leaflet and preparation method thereof |
abstract | The invention discloses a heart valve leaflet and a preparation method thereof. The heart valve leaflet has a three-layer structure, and the three-layer structure is a fiber layer, a sponge layer and a ventricular layer in sequence; the preparation material of the fiber layer includes a polymer and gelatin or collagen; the preparation materials of the sponge layer include polymers and polysaccharides; the preparation materials of the ventricular layer include polymers and silk fibroin; the polymers are selected from PLCL, PLA, PLGA, PCL and at least one of PU; the heart valve leaflet is in composition, and each layer component is similar to the natural heart valve component; structurally, the three-layer structure is obvious, similar to the three-layer structure of the natural valve leaflet; functionally It has suitable mechanical properties, can promote cell proliferation and adhesion, maintain cell viability, and can down-regulate the expression of calcification-related genes. Microenvironment. |
priorityDate | 2021-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.