| abstract |
The present invention relates to the technical field of medical materials, in particular to a light-cured forming composite hydrogel matrix precursor, a preparation method thereof, and a bracket with the same. The photocurable forming composite hydrogel matrix precursor includes methacrylated gelatin; sodium alginate; sodium carboxymethyl cellulose; chondroitin sulfate; wherein, photoinitiator: methacrylated gelatin: sodium alginate: The mass ratio of sodium carboxymethylcellulose: chondroitin sulfate is 0.2-0.3:8-10:1-3:0.6-0.8:0.05-0.07. Using the light-cured forming composite hydrogel matrix precursor extrusion 3D bioprinting technology can realize the cell-loaded printing hydrogel scaffold, the scaffold has controllable shape, good formability, high precision, and good stability; Good biocompatibility and biological activity can provide a good environment for fibroblasts to grow; the preparation process is simple and can be completed in a short time, and the porosity and mechanics of the 3D printed hydrogel scaffold can be adjusted by adjusting the ratio of raw materials performance. |