http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113663128-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-04 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-32 |
filingDate | 2021-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113663128-B |
titleOfInvention | High-strength composite coating artificial ligament and preparation method and application thereof |
abstract | The invention belongs to the technical field of artificial ligaments. The invention provides a high-strength composite coating artificial ligament, which comprises a composite coating and a shell-core structure artificial ligament; the composite coating comprises a calcium phosphate compound, polyurethane and an antibacterial agent; the shell-core structure artificial ligament comprises silk fibroin fibers and degradable fibers; the degradable fiber comprises one or more of polycaprolactone fiber, alginate fiber and polylactic acid fiber. The invention also provides a preparation method and application of the high-strength composite coating artificial ligament. The composite coating and the shell core structure effectively delay the degradation rate of the artificial ligament, improve the mechanical property of the artificial ligament, achieve the breaking strength of 60-80 MPa, and prolong the complete degradation time to 26 months. The composite coating artificial ligament has no cytotoxicity, no sensitization and irritation and excellent biocompatibility. |
priorityDate | 2021-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.