| abstract |
The invention provides a soft tissue repair patch material, a soft tissue repair patch and a manufacturing method and application thereof, and relates to the technical field of biological tissue repair. The soft tissue repair patch material includes sodium alginate/graphene hydrogel and fibrin/graphene hydrogel, wherein the sodium alginate/graphene hydrogel has a certain mechanical strength, and the degradation rate is relatively slow, which can Make up for the lack of mechanical properties of fibrin/graphene hydrogel and the fast degradation rate, so as to provide sufficient mechanical support and tissue repair time for the prepared soft tissue repair patch. Fibrin/graphene hydrogel is conducive to a large number of cells Amplification and reproduction, promotion of soft tissue repair, and the synergistic use of the above two hydrogel systems, so that the soft tissue repair patch made of the soft tissue repair patch material has mechanical properties suitable for clinical use and degradation matching tissue repair. It has a wide range of clinical application prospects due to its high speed and good cytocompatibility. |