| abstract |
The invention provides a method for synthesizing trimethylhydroquinone diester under the action of methyl radical reagent by using Pd-Rh as a reaction catalyst. The preparation method is as follows: (1) preparation of Rh catalyst: using a biaromatic heterocyclic compound as a ligand and rhodium trichloride as a substrate to synthesize a Rh catalyst; (2) using the Rh catalyst synthesized in (1) and palladium acetate as a The catalyst uses 2,6-dimethylphenol as a raw material, reacts under the action of a methyl radical reagent and an oxidant to synthesize a trimethylhydroquinone product, and then undergoes an acylation reaction to obtain a trimethylhydroquinone diester. The method uses low-cost 2,6-dimethylphenol as a raw material, uses a trace catalyst, has relatively excellent selectivity, avoids the use of a strong acid catalyst, and the reaction is relatively green and environmentally friendly, and is suitable for industrial scale-up production. |