abstract |
An adhesive conductive self-healing hydrogel that can be applied to a wound adhesive and a preparation method thereof, characterized in that the nucleophilic addition-elimination reaction of methacrylic anhydride and dopamine hydrochloride is carried out Obtain methacrylamidated dopamine (DMA), obtain acrylated guanine (GA) by reacting acryloyl chloride with guanine acid chloride, and prepare cytosine-grafted sodium alginate (SA-C) by EDC reaction ; Subsequently, an appropriate amount of SA-C, DMA, GA and AM monomers were dissolved in an aqueous solution to obtain a SA-GAD solution to form the first heavy G-C base pairing hydrogen bond dynamic network; mW/cm 2 ) under photopolymerization for 30 minutes to obtain SA-GAD hydrogel, forming the second heavy chemical cross-linking network; finally, soak the gel in calcium chloride solution for a suitable time to form the third heavy ionic cross-linking dynamic network. |