http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113640443-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f58c8a0d55a1bcf202bc0b6877fb530d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 |
| filingDate | 2021-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f59051c70dcc100bd9c1ac5850e86f47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_083d521ab44e0ed1c00b4b8fdd025457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03278dfdd2785735a57f883f87ab98e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dae77f87d77a5dbaa5161a597b67421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b62f9382fbfb39050f82157a1f977eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e57044b3f8b2f4e731e587b9852d4344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52ae11e6d04730956b3d4a98c5d034c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df93db90ad1f9d0f7e5703e7bbb31d2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92880aa9478c30f58417ee9dc5f99ef9 |
| publicationDate | 2021-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113640443-A |
| titleOfInvention | A kind of liquid chromatography determination method of dolutegravir |
| abstract | The invention belongs to the technical field of drug analysis, in particular to a liquid chromatography assay method for dolutegravir, wherein the assay method uses USP-L1 type octadecyl-bonded silica gel XBridge C18 as a stationary phase and a mobile phase A acid buffer salt ‑ Mobile phase B Acetonitrile ‑ Mobile phase C Methanol gradient elution as mobile phase, the resolution of each peak is above 2.0, the number of theoretical plates is above 2500 detectors for the content of dulutevir preparations, APIs, intermediates and impurities Determination; the dolutegravir liquid chromatography determination method in the present invention uses a diode array detector (PD), except that a chromatogram at a specified wavelength of 246 nm can be obtained, including retention time, peak height, peak area, area percentage, etc. At the same time, the peak purity can be displayed through the workstation software, indicating that the chromatographic peak is not separated, and the ultraviolet spectrum of a single peak can also be displayed, which plays a certain role in identification. |
| priorityDate | 2021-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.