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filingDate 2021-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113638221-B
titleOfInvention A kind of polyacrylonitrile fiber with biological activity and preparation method thereof
abstract The invention discloses a polyacrylonitrile fiber with biological activity, which is prepared by the following method: after hydrolyzing the polyacrylonitrile fiber in an alkaline solution, it is mixed with a collagen aqueous solution and a cross-linking solution, the pH value is adjusted, and chemical modification is carried out. The raw material of the alkaline solution includes NaHCO 3 , NaOH and water; the raw material of the cross-linking solution includes a cross-linking agent, a buffer substance and water; the collagen-modified polyacrylonitrile fiber contains collagen protein and polyacrylonitrile. The polyacrylonitrile fiber prepared by the method of the invention maintains the good natural structure of collagen, can better promote the adhesion and proliferation of fibroblasts, is conducive to the directional growth and functional expression of fibroblasts, and has good biocompatibility, The mechanical properties are beneficial to the repair of soft tissues, and are especially suitable for the mechanical strength requirements such as abdominal wall defects.
priorityDate 2021-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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