| abstract |
The invention discloses a zeolite composite nanozyme for tumor targeting, a preparation method and application thereof. 4-7 parts of endoribonuclease, 2-4 parts of endo-deoxyribonuclease, 1-2 parts of human serum albumin, 1-2 parts of glutathione, 2-3 parts of ferrous ammonium sulfate, azine The diammonium salt contrast agent is composed of 1-2 parts, the preparation method of the nano-drug is simple, the number of repeating units can be controlled by polymerization, the dosage ratio and concentration of the two polymers can be adjusted, and the loading amount of the bortezomib drug can be easily adjusted , In addition to chemotherapy by bortezomib, the nano-drug can also perform photothermal therapy and photoacoustic imaging. The synergistic effect of each part provides guidance for real-time diagnosis of tumor treatment process. |