http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113620872-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14
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filingDate 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25b3663ec042f7682897d4e13dafccf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dedfe3d402bc4953fa57768196663e34
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publicationDate 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113620872-A
titleOfInvention A kind of preparation method of 2-quinolinyl phenyl ketone compound
abstract The invention discloses a method for preparing a 2-quinolinyl phenyl ketone compound. Using 2-ethynyl aniline, phenylglyoxal and piperidine as starting materials, a three-component coupling reaction (A) is catalyzed by gold. 3 couplings) and intramolecular condensation reaction to synthesize 2-quinolinyl phenyl ketone in one step. The preparation method has cheap and easily available raw materials, simple operation steps, mild reaction conditions, high atom economy and excellent regioselectivity, and is suitable for the needs of large-scale industrial production. The prepared 2-quinolinyl phenyl ketone is an important active drug molecule and can be used as a cannabinoid CB 2 receptor agonist.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115504911-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115504911-A
priorityDate 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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