| abstract |
The invention discloses a method for synthesizing alkenyl nitrile. Or alkynes, alkalis, and the reaction kettle is charged with CO and H 2 , and the reaction is heated after the reaction, and the alkenyl nitrile compounds are obtained through the hydroformylation reaction and the Knoevenagel reaction mechanism. Among them, nitrile substrates have a wide range. The para- and meta-substituents of the aryl group in phenylacetonitrile are electron withdrawing groups or electron donating groups, which can achieve good results, and can also be achieved by replacing aryl groups with heterocycles. . The reaction conditions of the method are mild, the operation is simple, the raw materials are easily obtained, the substrates come from a wide range, and can be converted into various other useful molecules, which has strong practicability. |