http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113616860-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-41 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
filingDate | 2021-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113616860-B |
titleOfInvention | A vascular stent coating material with drug sustained release, anticoagulation and anticalcification properties and preparation method thereof |
abstract | The invention provides a vascular stent coating material with drug sustained release, anticoagulation and anticalcification properties and a preparation method thereof. The preparation method includes the following steps: preparing a macromolecular carrier capable of effectively assembling anticalcification drugs; The functional component is compounded with the macromolecular carrier to prepare an intermediate carrier encapsulating the anti-calcification component; the intermediate carrier is used as a cationic carrier, and the modified chitosan and heparin molecules are used as polyelectrolyte components respectively. The coating is prepared on the surface of the vascular stent by means of the method; the single-cycle "modified chitosan/intermediate carrier/heparin" composite coating is defined as 1 layer, and through 1-20 cycles of spraying, spin coating or dip coating operations, get the target coating. The coating obtained by the invention can be used for the modification of vascular stent materials, so that the vascular stent can obtain long-acting drug release, anticoagulation, anti-proliferation and anti-calcification properties, and effectively inhibit the re-atherosclerosis and calcification in the stent after implantation. evolution. |
priorityDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.