| abstract |
The invention discloses a preparation method of magnetically responsive alprostadil microspheres. Polylactic acid-glycolic acid copolymer (PLGA)-alprostadil microspheres are prepared by a double emulsification-solvent evaporation method, and then an electrostatic adsorption self-assembly method is used. , the magnetically responsive alprostadil microspheres are prepared, and the magnetically responsive alprostadil microspheres have a drug loading of 3.2 wt.%, a coating rate of more than 70%, and a drug release rate of more than 80%. |