http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113607534-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-31 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 |
| filingDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113607534-B |
| titleOfInvention | Dyeing method, kit and application |
| abstract | The present invention relates to a dyeing method, kit and application. The present invention combines Papanicolaou staining on the basis of P16 INK4a immunocytochemical staining, improves and adjusts the staining steps, adopts a fixative containing glacial acetic acid and acetone, and uses a combination of permeabilizing agent I-permeabilizing agent II at the same time The permeabilization method replaces high-pressure repair, effectively eliminating the background and non-specific coloring. The cell smear stained by this method can simultaneously observe the results of P16 INK4a immunocytochemical staining and the morphological structure of cells on the same section, which increases the information content of a single film and avoids the subjectivity and uncertainty of relying only on morphology improve the repeatability of the results and the accuracy of interpretation. The present invention further provides a kit for the combined staining of P16 INK4a immunocytochemical staining and Papanicolaou staining, which is helpful for realizing digital automatic reading and has significant economic and social benefits. |
| priorityDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.