Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a3f59290f6caa361d490175d4661ead |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y201-01004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y602-01001 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
filingDate |
2021-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a4db8e05a4793ced500693604eb2a0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bea9df2ccb2223c62e8a95ab782721e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_911655d9cb66fc5bb32763e7801f38ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d981e0d356932ae1497b03734d3b14c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c62e2959b687ef657ad34fac3a250cb2 |
publicationDate |
2021-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-113604521-A |
titleOfInvention |
Method for enhancing yield of N-acetyl-5-hydroxytryptamine |
abstract |
The invention relates to a method for enhancing the yield of N-acetyl-5-hydroxytryptamine. Converting a substrate 5-hydroxytryptamine by a recombinant cell containing a functional gene related to catalyzing 5-hydroxytryptamine to generate N-acetyl-5-hydroxytryptamine to obtain N-acetyl-5-hydroxytryptamine, and expressing an N-acetyl-5-hydroxytryptamine transferase gene or an acetyl coenzyme A synthetase gene for enhancing the yield of N-acetyl-5-hydroxytryptamine by the recombinant cell containing the functional gene related to catalyzing 5-hydroxytryptamine to generate N-acetyl-5-hydroxytryptamine, so as to produce N-acetyl-5-hydroxytryptamine transferase and acetyl coenzyme A synthetase. According to the invention, through overexpression of the AANTA gene and the ACS gene, the generation of N-acetyl-5-hydroxytryptamine from 5-hydroxytryptamine serving as an AANAT catalytic substrate is enhanced, and the synthetic yield of the N-acetyl-5-hydroxytryptamine is obviously improved. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115806891-A |
priorityDate |
2021-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |