| abstract |
The present invention relates to a hydrophobic macromolecule hemostatic repair material, its preparation method and application. The repair material can quickly adhere to the wet tissue interface, and it comprises a component A and a component B, wherein the component A includes a catalytic unit and a tissue interface. Linking agent, component B includes a flowable hydrophobic macromolecule and a coupling unit; the catalytic unit and the coupling unit constitute a forming agent. The hydrophobic macromolecule hemostatic repair material of the present invention realizes fast adhesion to the wet tissue interface by virtue of the strong drainage ability of the hydrophobic macromolecule, the rapid underwater gel-forming ability of the forming agent and the cross-linking reaction of the tissue cross-linking agent on the tissue interface. The invention provides a hydrophobic polymer hemostatic repair material, which has good tissue adhesion, strong plasticity, and good biocompatibility, and can effectively promote the repair and healing of wounds and wounds. It has good clinical application prospects in hemostasis and repair of other tissues and organs. |