http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113599369-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2021-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113599369-B |
| titleOfInvention | A kind of anti-oxidative stress nano reagent and its preparation method and application |
| abstract | The present application relates to an anti-oxidative stress nano-reagent and its preparation method and application, the method comprising: preparing diselenic acid solution, N-hydroxysuccinimide solution and 1-(3-dimethylaminopropyl)-3 ‑Ethylcarbodiimide hydrochloride solution and mixed; add protein solution to the above solution and mix, then add buffer, then add astaxanthin solution, mix and stir for 20‑24h. The method is simple, easy to operate, and has high yield and yield, and can be produced in large quantities; astaxanthin is tightly wrapped in the cavity structure formed by hydrophilic diselenic acid and protein, which improves the production of astaxanthin. The solubility, stability, and biosafety and drug loading in aqueous and lipid solvents increase the therapeutic dose and bioavailability; the nano-agent also has the ability to target inflammation sites, controllable drug release, and dual anti-oxidation The advantage of this method greatly improves the efficiency of anti-inflammation, which can reduce the abuse of clinical antibiotics, improve the cure rate of inflammation and reduce the recurrence rate. |
| priorityDate | 2021-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.