http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113563394-A

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filingDate 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60ba462a0a33d566e776ca6e8ce9d57b
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publicationDate 2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113563394-A
titleOfInvention A kind of preparation method of chitosan oligosaccharide monomer
abstract The invention discloses a preparation method of chitosan oligosaccharide monomer. The present invention pretreats the chitosan oligosaccharide solution, so that the high-concentration chitosan oligosaccharide solution is graded and precipitated in 80-90% ethanol solution, the chitosan oligosaccharide with a high degree of polymerization is precipitated, and the chitosan oligosaccharide with a small degree of polymerization remains in the supernatant In the liquid, the precipitation is processed for the second time, the supernatants obtained from the two times are combined, concentrated by rotary evaporation, and the concentrated solution is freeze-dried to obtain a crude chitosan oligosaccharide with a high polymerization degree of 1-5. Then carry out cation exchange chromatographic separation, adopt staged isocratic elution, one eluent concentration only elutes one degree of polymerization of chitosan oligosaccharide, the separation process does not need to be detected, the purity of the obtained chitosan oligosaccharide monomer reaches more than 90%, and the yield is to the gram level.
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priorityDate 2021-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 40.