| abstract |
The present invention relates to the technical field of biological chips, in particular to a novel high-throughput closed microarray printing system, comprising: a microarray printing module, including a microarray printing plate and a temperature control unit, used for preparing nucleic acid in a solution from a microarray, Provide an optimal adsorption temperature when proteins, etc. are printed on the surface of the chip; the microarray printing liquid circuit system, including the sample addition pump, the liquid supply pump and the valve, is used to continuously add a fixed volume of microarray preparation solution to the microarray printing module; Microarray printing motion system for moving microarray printing modules. The invention can improve the homogeneity among the microarray spots, avoid cross-contamination among the spots, especially increase the protein immobilization amount of the spots in the protein microarray, so as to break through the bottleneck restricting the development of the biochip. |