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filingDate 2021-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113559720-B
titleOfInvention Polyethersulfone hemodialysis membrane with heparin-like modified coating and preparation method and application thereof
abstract The invention relates to a polyethersulfone hemodialysis membrane with a heparin-like modified coating and a preparation method and application thereof. Firstly, the polyethersulfone hemodialysis membrane was soaked in alcohol solvent, then taken out and soaked in a modified solution composed of water-soluble monomers containing carboxyl groups and water-soluble polyphenols, and then taken out and soaked in water-soluble water-soluble monomers containing sulfonic acid groups. In the monomer modification solution, it can be finally taken out, washed and dried. The invention constructs a heparin-like modified coating loaded with carboxyl groups and sulfonic acid groups on the surface of the hemodialysis membrane through the covalent reaction of amino groups, sulfhydryl groups and catechol on polyphenols and the self-polymerization deposition and adhesion of polyphenols. layer, thereby significantly improving the hydrophilicity, blood compatibility and fouling resistance of the membrane material.
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