Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c094c8526b300120081f9f27c0ba8f7c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2037-0053 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24069 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
filingDate |
2021-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7038411f3c419bc85d5923d557da52bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_184a058e286772b7a9d8c91fa4f3dc75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_655545424d9d78324ce17406495df523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f3ee6d9b975df135fb3d677dd6f26f |
publicationDate |
2021-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-113559251-A |
titleOfInvention |
Soluble micro-needle patch and preparation method and application thereof |
abstract |
The invention provides a soluble microneedle patch, a preparation method and application thereof. The microneedle patch comprises a main body support component and sustained-release microspheres, wherein the main body support component consists of a needle body and a base layer. The neurotoxin sustained-release microspheres are prepared from functional components and a biocompatible high polymer material and are coated in the needle body; the needle body is prepared from a hydrophilic high molecular polymer and magnesium particles; the base layer is prepared from antibacterial high polymer materials. The functional component is botulinum toxin A. The microneedle patch disclosed by the invention effectively penetrates the stratum corneum barrier of the skin, and as the hydrophilic high polymer material is quickly dissolved in the skin, the slow-release microspheres containing the effective components are implanted into the dermis layer for long-term effective component slow release, so that long-term treatment of diseases is realized. |
priorityDate |
2021-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |