http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113552236-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_509dcdee307c173971b32910685d906e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-047 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2020-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40e56371d83cb2bcaebfa35135c7ce6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15fd53c8e83b0069e815ca2050659a8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_633b4928475db6554e5cbf746f77d0ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcccad651088020612213148dff0583b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7ef52b6517d33146613fb7c59e3f19f |
publicationDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113552236-A |
titleOfInvention | Method for detecting methyl isocyanate in temozolomide |
abstract | The invention discloses a method for detecting methyl isocyanate in temozolomide, which comprises the following steps: preparing a reference substance solution, precisely measuring methyl isocyanate, placing the methyl isocyanate in a volumetric flask, diluting with acetonitrile to a constant volume to a scale, and preparing the reference substance solution; step two, preparing a test sample solution, precisely weighing the temozolomide raw material medicine, adding acetonitrile, shaking until the solid is dissolved, and preparing the test sample solution; measuring, namely precisely measuring a test solution and a reference solution, injecting a sample, performing separation analysis by using a gas chromatograph-mass spectrometer, and recording a spectrogram; and step four, calculating, namely calculating the content of the methyl isocyanate in the test sample solution by using a peak area according to an external standard method. The method has the characteristics of simple process, low use cost, good precision, high accuracy and the like, and can quickly determine the content of methyl isocyanate in temozolomide. |
priorityDate | 2020-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.