http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113549076-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 |
filingDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113549076-B |
titleOfInvention | A kind of multi-substituted purine compound and its preparation method and application |
abstract | The invention discloses a multi-substituted purine compound represented by formula (I) and its pharmaceutically acceptable salt, its preparation method and application. The present invention also discloses that the above-mentioned compound has obvious inhibitory effect on RNA adenosine deaminase 1 (ADAR1), and can be used for preventing and/or treating cancer or tumor-related diseases caused by abnormal activity of this enzyme, especially Prostate cancer, leukemia, breast cancer, multiple myeloma, lung cancer, gastric cancer, ovarian cancer, colon cancer, liver cancer, pancreatic cancer and human glioma and other diseases. |
priorityDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.