http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113549028-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D293-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D293-10 |
| filingDate | 2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113549028-B |
| titleOfInvention | 5-halogen-6-nitrobenzselenadiazole derivative and preparation method and application thereof |
| abstract | The invention belongs to the technical field of chemical synthesis, and particularly relates to a 5-halogen-6-nitrobenzselenadiazole derivative, and a preparation method and application thereof. The 5-halogen-6-nitrobenzselenadiazole derivative has small molecular weight and no chiral center; experiments prove that the compound has obvious anti-tumor activity, can effectively inhibit the growth and proliferation of various tumor cells, has obvious inhibition effect on the migration, crawling and cloning of the tumor cells, and can make the tumor cell cycle blocked at the G1 stage to induce the apoptosis of the tumor cells. Meanwhile, the preparation method of the 5-halogen-6-nitrobenzselenadiazole derivative is simple, the operation steps are few, the raw materials are easy to obtain, the solvent is green and environment-friendly, and the product is easy to separate and purify, so that the derivative has a wide biological medicine application prospect. |
| priorityDate | 2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.