http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113548982-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0239 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0204 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 |
| filingDate | 2021-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113548982-B |
| titleOfInvention | Preparation method of 4-cyano-2-fluorobenzyl alcohol |
| abstract | The invention discloses a preparation method of 4-cyano-2-fluorobenzyl alcohol, and belongs to the technical field of medical intermediates. 3, 4-difluorobenzonitrile is adopted as a raw material and reacts with potassium bromide in the presence of a phase transfer catalyst, or 3-fluoro-4-bromobenzaldehyde and hydroxylamine are adopted for dehydration reaction to obtain 3-fluoro-4-bromobenzonitrile, and then Grignard reagent exchange and paraformaldehyde react to obtain 4-cyano-2-fluorobenzyl alcohol. The method is safe and stable, and the obtained product is easy to purify and has potential industrial amplification prospect. |
| priorityDate | 2021-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.