| abstract |
Prevention, alleviation or elimination of male androgen deficiency symptoms in susceptible warm-blooded animals (including humans) or symptoms associated with male hypogonadism and the occurrence of diseases associated with low serum testosterone and/or low DHEA or low androgens Novel methods of high rates of treatment comprising administering sex steroid precursors, in particular dehydroepiandrosterone (DHEA) and selective estrogen receptor modulators (SERMs) (in particular acolbifene), antiestrogens or prodrugs of both. Symptoms or diseases are loss of libido, erectile dysfunction, fatigue, loss of energy, depression, bone loss, muscle weakness, fat accumulation, dementia, loss of body hair, fertility problems, gynecomastia, anemia, and decreased well-being. The present invention also discloses pharmaceutical compositions for delivering active components and kits. |