http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113546044-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
filingDate | 2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113546044-B |
titleOfInvention | Lurasidone self-microemulsion composition and preparation method thereof |
abstract | The invention belongs to the technical field of medicines, and particularly discloses a lurasidone self-microemulsion composition and a preparation method thereof, wherein the lurasidone self-microemulsion composition comprises, by weight, 0.1-20 parts of lurasidone, 5-70 parts of an oil phase, 10-70 parts of an emulsifier, and 0-50 parts of a co-emulsifier; the lurasidone self-microemulsion composition forms and releases a microemulsion when contacted with an aqueous medium. The lurasidone free alkali is used as a raw material medicine to prepare the lurasidone self-microemulsion composition, so that the solubility of fat-soluble auxiliary materials is improved, the drug loading rate of a self-microemulsion carrier is improved, and gastrointestinal irritation and other side effects are reduced. |
priorityDate | 2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.