http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113533714-A

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filingDate 2020-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_219ebf342c75e6a43dc14059b4854fae
publicationDate 2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113533714-A
titleOfInvention Preparation of MCM5/NMP22 double-index immunochromatography kit
abstract The invention particularly relates to an immunochromatography kit for simultaneously detecting Minichromosome maintenance protein5 (MCM 5) and Nuclear matrix protein22 (NMP 22), which mainly comprises an immunochromatography test strip, wherein the immunochromatography test strip is formed by sequentially adhering a sample pad, a binding pad, a nitrocellulose membrane and absorbent paper on a PVC (polyvinyl chloride) bottom plate. Wherein, the combination pad adsorbs MCM5 antibody-microsphere and NMP22 antibody-microsphere, the nitrocellulose membrane fixes MCM5 antibody to form a detection line 1(T1 line), fixes NMP22 antibody to form a detection line 2(T2 line), and fixes anti-IgG antibody to form a quality control line (C line). The invention also discloses a process for coupling the MCM5 antibody and the NMP22 antibody to the microspheres. The invention establishes an MCM5/NMP22 immunochromatographic kit, simultaneously detects the concentration of MCM5 and NMP22 in urine, and is used for screening early bladder cancer and monitoring prognosis and recurrence of bladder cancer.
priorityDate 2020-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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