abstract |
The present invention relates to an amphiphilic phosphorus-containing tree crown macromolecular material and its preparation and application. The structure of the amphiphilic phosphorus-containing tree crown macromolecular material is shown in formula I. The raw materials of the invention are commercialized, the preparation method is simple, and the operation is easy. On the one hand, the prepared nanocomposite can cause the death of immunogenic tumor cells and increase the proportion of cytotoxic T cells, and on the other hand, can promote the proliferation of natural killer cells in the body, so as to achieve Remodeling the tumor microenvironment and enhancing the purpose of anti-tumor immunotherapy has a good application prospect in the field of tumor therapy. |