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filingDate 2021-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113522049-B
titleOfInvention A method for concentrating silk fibroin solution by using selective permeation liquid-absorbing membrane
abstract The invention discloses a method for concentrating a silk fibroin solution by using a selectively permeable liquid-absorbing membrane. The method adopts blue light initiators, crosslinking agents, onium salts, hydrophilic monomers, etc. Combined reaction to prepare selectively permeable liquid-absorbent membrane. After repeated water absorption swelling-evaporative dehydration, the residual photoinitiator, onium salt, and unreacted monomer or uncrosslinked polymer segment are removed, and finally a permeable liquid-absorbent membrane material with a stable crosslinked structure is obtained. The osmotic liquid-absorbing membrane selectively absorbs the water in the silk fibroin solution and repels the silk fibroin with the same charge, so as to realize the effective concentration of the silk fibroin solution. Compared with the prior art, the preparation method of the present invention is simple and easy to operate, and the prepared osmotic liquid-absorbing membrane can be reused many times, and has good application prospects in the fields of biomedicine and tissue engineering.
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