http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113521378-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f611256b6c97b9be6793dc6bf793ddf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-04 |
| filingDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7057d9f52ae2afd00d01aaf5eb2294ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_225a847efe957b90189edfe60bfa5d00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c77832c25ed4465381f4320e75f4a30 |
| publicationDate | 2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113521378-A |
| titleOfInvention | A kind of preparation method of porous microsphere and microsphere embolizing agent obtained thereby and application thereof |
| abstract | The invention relates to a method for preparing porous microspheres, which comprises: S1, dissolving ethylene glycol polymer and polyvinylpyrrolidone in purified water, stirring and dissolving, adding N,N-methylene acrylamide, and then adding methyl Ethyl acrylate is dissolved to provide an aqueous phase; S2, liquid paraffin is added to petroleum ether, and tetramethylethylenediamine is added to provide an oil phase; S3, under stirring, the aqueous phase is added dropwise to the oil phase, rapidly Stir for 1-4h, heat up to 40-60°C, continue to stir for 2-5 hours, and filter to obtain porous microspheres. The present invention also relates to the thus obtained microsphere embolic agent and its application. According to the preparation method of the porous microspheres of the present invention, the porous microspheres are obtained by dripping the water phase into the oil phase, which are micro-scale spherical structures with a porous structure on the surface, so as to "adsorb and embed" various microspheres through the pores on the surface. Molecules such as anti-tumor drugs are placed in microspheres to achieve better drug loading effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023000825-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114533938-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114344554-A |
| priorityDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.