http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113521305-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7c7afaefa27424bbf2a16a10053f54e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6949 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2021-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03d10946f681297383cdaedc66f0ca28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_143283a75da97c5c7615572d2e14ebe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd0c03f28d65daa68623514e4fbcd882 |
| publicationDate | 2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113521305-A |
| titleOfInvention | Propolis alcohol extract-cyclodextrin-chitosan-mucin sustained-release gel as well as preparation method and application thereof |
| abstract | The invention provides a propolis alcohol extract-cyclodextrin-chitosan-mucin sustained-release gel and a preparation method and application thereof, belonging to the technical field of sustained-release medicines. The invention cross-links and compounds sodium carboxymethylcellulose-mussel mucin polymer and propolis alcohol extract wrapped by cyclodextrin-chitosan, wherein the catechol structure of mussel mucin can be oxidized into an o-quinone structure under alkaline or oxidation conditions, and the o-quinone structure is combined with active amine groups on the surface of mussel chitosan to form a stable slow release structure through Schiff base-like reaction, so that on one hand, the gel is ensured to be attached to an ulcer surface to form a long-term protection and administration system while being rapidly gelled, and on the other hand, the unique porous elastic structure of the mussel chitosan realizes gradual slow release of the propolis alcohol extract, and the propolis alcohol extract continuously acts on the ulcer, and has better clinical effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114808465-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116036360-A |
| priorityDate | 2021-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.