| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_338122610c66aec3edaa563d6ecc7b71 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a67c3e03cf62663da3bc1d236c29f0b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7025568937293249137dcf84536a18dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f052dfe27e169e67f04a187a33fccc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89c0b5955db471db28788536ad8fc7f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f576a287da454db03b7901ab587e3176 |
| publicationDate |
2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113521291-A |
| titleOfInvention |
Application of the ZNF143-MDIG-CDC6 axis in hepatocellular carcinoma |
| abstract |
The invention provides the application of a ZNF143-MDIG-CDC6 axis in hepatocellular carcinoma. Specifically, the present invention provides an active ingredient combination and its use for synergistic treatment of liver cancer, the active ingredient combination comprises the first active ingredient zinc finger protein ZNF143 inhibitor, the second active ingredient cell division cyclin CDC6 inhibitor, and/or a third active ingredient mineral dust-inducible gene MDIG inhibitor. The method of the present invention can effectively inhibit the development and metastasis of hepatocellular carcinoma. |
| priorityDate |
2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |