http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113520656-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf415258683635c3e869f8fdd14bb250
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61D1-00
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61D1-00
filingDate 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7914dd7b3765f0d1d8f17fac4343e14c
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publicationDate 2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113520656-A
titleOfInvention Cornea new blood vessel/lymphatic vessel generation damage model and construction method and application thereof
abstract The invention provides a cornea neovascularization/lymphatic vessel generation injury model and a construction method and application thereof. The model is constructed by adopting a mode of combining corneal epithelium mechanical scraping and biological adhesive bonding of corneal sutures on corneal stroma on the basis of the idea of corneal sutures, so that the problems of high molding difficulty and low efficiency when the corneal suture model is applied to small rodents are solved, common reasons of molding failure caused by corneal perforation, suture falling and the like are avoided, and the advantages of more regular growth of neovascular corneal sutures, avoidance of influence of chemical reagents in a chemical induction method, single and controllable damage mode and the like are retained. In addition, the model-based construction method can be used as a novel effective model for mouse and rat cornea neovascularization or lymphangioleiomy, and is simple, effective and controllable, so that the model is high in applicability.
priorityDate 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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