| abstract |
The invention provides a method and application for qualitative and quantitative detection of torasemide illegally added to food, the method comprising: preparing a sample to be tested and a standard solution of torsemide; adopting high performance liquid chromatography-tandem The mass spectrometer was used to measure the sample to be tested and the standard solution respectively; the chromatographic retention time of each compound in the food sample and the standard solution was recorded, and the percentage relative to the abundance of the strongest ion was used as the relative abundance of the qualitative ion pair, and the concentration of the same compound to be tested was recorded. The relative ion abundance of the corresponding components in the sample and the standard solution; when the sample to be tested detects a chromatographic peak that is consistent with the retention time of the chromatographic peak of the torasemide standard, determine the corresponding compound and content in the sample to be tested. The detection method of the invention has the advantages of simple and rapid pretreatment, strong specificity and high sensitivity, can simultaneously perform qualitative and quantitative analysis on torasemide in food such as tablet candies, biscuits, beverages, oral liquids, tea beverages and the like, and can be applied to food Screening for illegal addition of torasemide in safety regulation. |