| abstract |
The invention discloses an efficient and environment-friendly synthesis method of isolongifolinone. The synthesis method is as follows: Step 1: material preparation: the materials include isolongolene, concentrated sulfuric acid, hydrogen peroxide solution, petroleum ether, anhydrous sulfuric acid Sodium, methanol, toluene, salt water, sodium hydroxide solution; Step 2: place isolongifole and concentrated sulfuric acid in a reaction kettle, stir and heat to react, and drop a hydrogen peroxide container, dropwise and keep warm; Step 3: Transfer: stop heating and stirring, and transfer the reactant to the separatory funnel; Step 4: Extraction: add saturated brine to the separatory funnel, and extract; the beneficial effects of the present invention are: using hydrogen peroxide as The oxidant will not produce waste residue and waste gas after the reaction, which improves the green environmental protection effect of isolongifolin synthesis; helps to reduce the usage of concentrated sulfuric acid, reduces the cost of synthesizing isolongifolinone, and has good promotion value . |