| abstract |
The invention belongs to the technical field of biomedicine, in particular to an antibacterial colloid applicator for wound healing and a preparation method thereof, including an antibacterial colloid applicator for wound healing, and an antibacterial colloid applicator for wound healing comprising medical grade polyvinyl alcohol/ Oxidized dextran (PVA/ODex) colloidal matrix layer, resveratrol-hydroxypropyl-β-cyclodextrin-histone-1-rich slow-release microspheres, film backing, non-woven fabrics, adhesives and The release paper and the antibacterial colloid for wound healing are applied in a square structure. The present invention selects medical grade polyvinyl alcohol and oxidized dextran as raw materials, and adopts microwave freeze-thaw method to assist cross-linking to prepare PVA/ODex colloid matrix. Res has the ability to resist oxidation and promote vascularization, and His-1 can promote endothelial cell adhesion, migration and vascularization. The two are loaded into PVA/ODex colloid matrix through the microsphere drug-loading system to play a role together for skin acute Wound healing and burn and scald treatment, the wound healing effect is optimistic and efficient. |