http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113501905-A

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filingDate 2021-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c689561aec596ca6b78cdb21339eed1
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publicationDate 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113501905-A
titleOfInvention Preparation method of light-responsive DNA hydrogel based on light-induced proton transfer process
abstract The invention provides a preparation method of a light-responsive DNA hydrogel based on a light-induced proton transfer process. Under light stimulation, photoacid groups release protons and are captured by proton-sensitive DNA structures, resulting in changes in the DNA structure, thereby triggering the The DNA-structured hydrogel undergoes a transition from solution to gel state or from gel to solution state; under UV light irradiation, the photoacid generator modified on acrylamide/DNA copolymer releases hydrogen ions, enriching cytosine sequences After DNA is combined with hydrogen ions, an intermolecular or intramolecular i-motif quadruplex structure is formed, and the copolymer chain can be cross-linked or dissociated accordingly to realize the corresponding phase transition process under illumination conditions. Copolymerization of oligomer, acrylamide and modified unsaturated double bond DNA to realize the construction of light-responsive DNA hydrogel based on light-induced proton transfer process, the process cost is low and the operation is simple. It has certain application prospects in the fields of , driver and drug release.
priorityDate 2021-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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