http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113501871-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-605 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-605 |
filingDate | 2021-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113501871-B |
titleOfInvention | A kind of method for preparing darcy glucagon by solid-liquid phase combination |
abstract | The invention discloses a method for preparing darcy glucagon by solid-liquid phase combination. The invention adopts the liquid-phase method for the first time to synthesize monomers Boc-His(Trt)-Ser(tBu)-Gln(Trt)-OH, Fmoc-Gly ‑Thr(tBu)‑OH, Fmoc‑Leu‑Asp(OtBu)‑OH, Fmoc‑Ala‑Arg(Pbf)‑OH, Fmoc‑Ala‑Glu(OtBu)‑OH, Fmoc‑Val‑Lys(Boc)‑ OH, Fmoc-Leu-Glu(OtBu)-OH, and then use the above monomers as raw materials to prepare darcy glucagon in solid phase. The invention can effectively improve the purity of the crude peptide, reduce the difficulty of purification, improve the yield of the final product, is beneficial to the large-scale industrial application of the synthesis scale, and reduces the production cost. |
priorityDate | 2021-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.