http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113501783-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-24 |
| filingDate | 2021-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113501783-B |
| titleOfInvention | A kind of erianin heterocyclic derivative and its preparation method and application |
| abstract | The present invention relates to an Erianin heterocyclic derivative and its preparation method and application, wherein the structural formula of the Erianin heterocyclic derivative is: Wherein, X is O or NH; R is a furyl heterocyclic substituent, a thienyl heterocyclic substituent, a thiazolyl heterocyclic substituent, a pyrimidinyl heterocyclic substituent, a pyridazinyl heterocyclic substituent, a nicotinyl heterocyclic substituent, One of ring substituents and indolyl heterocyclic substituents; the preparation method includes: condensation reaction of erianin with a carboxylic acid compound containing substituent R; or 4-methoxy-3-nitrobenzene Formaldehyde and 3,4,5-trimethoxy-triphenylbenzyl bromide phosphine salt are used as raw materials, and after Wittig reaction and reduction reaction, condensation reaction is carried out with a carboxylic acid compound containing substituent R to obtain the above-mentioned Maolan Heterocyclic derivatives. Compared with the prior art, the present invention connects erianin with heterocyclic compounds such as nicotinic acid through ester bonds to form a twin drug, and provides a new way for improving the pharmacological activity of erianin. |
| priorityDate | 2021-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.